The reality star, 47, took to Instagram on Thursday to announce that she is returning to Broadway to star in Chicago.
"I'm so excited to say I am headed back to BROADWAY in CHICAGO as Matron Mama Morton!" she wrote. "#neneismama #doingwhatilove #broadwaybaby #movingbacktonework."
Leakes will play Matron "Mama" Morton, who was played by Queen Latifah in the 2002 film adaptation.
The former Real Housewives of Atlanta star's run will begin on Nov. 23 and last until Dec. 20.
Leakes made her Broadway debut last year as the wicked stepmother in Cinderalla.